Thursday 22 March 2012

Tuesday 13 March 2012

To prescribe or not to prescribe?


Looking after the elderly, particularly in care homes, has been a hot topic recently as we debate the future of our ageing population and reform of the NHS. Thus it has become more important than ever that we provide a standard of care for the elderly that is both effective in providing high- quality care and value for money.
                Many patients in care homes are affected by dementia, which is not surprising since the onset is a direct consequence of age. Non- pharmacological treatments are usually the first line of treatment for patients with dementia, but often the symptoms are severe enough to warrant treatment with anti- psychotics, and as a consequence around one third of patients suffering from dementia in care homes are treated with anti- psychotics.
                But are we failing to provide an acceptable standard of care by prescribing so many drugs? New research carried out in the US suggests that this may be the case. Huybrechts et al utilised the Medicaid database (a database of medical benefits) to examine the mortality rates of patients over 65 receiving anti- psychotic treatment for dementia in care homes between 2001 and 2005. They found that patients who were receiving treatment with haloperidol had double the risk of morbidity compared with patients receiving although they were less likely to exhibit psychiatric symptoms.
                This paper appears to be making an important point: that prescribing anti- psychotics to dementia patients is actually detrimental to their health and is increasing mortality in care homes. However, the research is crying out for a control that is not another anti- psychotic treatment and that more closely resembles more conventional standards of care. This paper can inform us of differences in the number fatalities between different anti- psychotics, but lacks the design to tell us that patients taking these drugs are worse off than those on other treatments (as was claimed by the BBC).
                This paper does send an informative message- that prescribing already fragile elderly patients powerful anti- psychotics with potentially debilitating side effects is an ill-advised strategy in many cases. However, we need further research with study designs that are able to show us the bigger picture, as well as research into a legitimate alternative to taking anti- psychotics before we can make decisive changes in policy. Sadly, this prospect  is probably further off than we think.

original paper (open access):